What do you know about f-MRI? Discuss how it is beneficial in ENT practice?

  • Functional magnetic resonance imaging techniques.
  • This technique relies on the fact the cerebral blood flow and neuronal activation are coupled. When an area of the brain is active, blood flow to that reason also increases.
  • The most robust and widely used f-MRI method is BOLD f-MRI (Blood oxygenation level development f-MRI)
    • In BOLD f-MRI the imaging contrast: arises as a consequence of the higher ratio of oxy-to deoxy-Hb in local capillaries and draining vessels with brain activity.
    • When bound to O2, Hb is diamagnetic in which magnetic flush is reduced resulting in the repelling of the applied magnetic field.
    • When Hb is deoxygenated it is paramagnetic in which magnetic flux is increased and the applied magnetic field is attracted into the maternal.
    • Thus a change in Hb oxygenation leads to change in the local distortion of a magnetic field applied to it. These signals can be recoded as (BOLD contrast).
    • If deoxygenation ↓→↑ higher signal interstices (↑↑BOLD) Higher the tissue activity, ↓↓ concentration of oxyhaemoglobin →↓↓BOLD.

Application of f-MRI are growing rapidly and potentially have relevance to several aspects of otolaryngology There are:

  1. It can be successfully used in patient screening before cochlear implant surgery.
  2. It provides better spatial resolution
  3. There is no need of contrast enhancement.
  4. This can be easily performed to study audiology physiology by stimulation auditory center.


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