HNSCC cell secrete immunoregulatory cytokines IL-2, IL-4, IL-6 These IL effect growth inhibition directly or indirectly E.g. Local treatment with IL-2 given transmural injection in recurrent HNSCC: positive response IL-2
Tag: HNSCC
ETIOLOGY OF HNSCCETIOLOGY OF HNSCC
Carcinogens Viral Familial risk Iron deficiency anaemia Molecular epidemiology CARCINOGENS: Cigarette: releases polycyclic aromatic hydrocarbons which are broken down by aryl hydrocarbon hydroxylase to produce carcinogenic epoxide. These binds to