DIFFERENTIAL DIAGNOSIS OF SKIN CHANGES AROUND NIPPLE OF BREAST

1. If nipple skin changes and areola area e.g. eczematous changes or inflammatory changes then it’s likely to be Paget’s disease, especially if unilateral: Go for open biopsy or punch biopsy.
2. If nipple is retracted or peu de orange or ulcerates then breast cancer is the likely diagnosis.
3. If there is ulcer on the breast, ulcer always means cancer until proven otherwise: Do biopsy.