- HNSCC cell secrete immunoregulatory cytokines IL-2, IL-4, IL-6
- These IL effect growth inhibition directly or indirectly
- E.g. Local treatment with IL-2 given transmural injection in recurrent HNSCC: positive response
- IL-2 and IL-4 increase T cell and NK cells within tumour.
IMMUNOTHERAPY IN TREATMENT OF HNSCC
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